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NHS Foundation Trust  
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 Formulary Chapter 10: Musculoskeletal and joint diseases - Full Chapter
10.01.03  Expand sub section  Drugs which suppress the rheumatic disease process
10.01.03  Expand sub section  Gold
10.01.03  Expand sub section  Penicillamine
10.01.03  Expand sub section  Antimalarials
10.01.03  Expand sub section  Drugs affecting the immune response to top
Abatacept (Orencia®)
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Formulary
NICE Formulary
High Cost Medicine
Abatacept 125mg pre-filled syringe (Orencia®)
Abatacept 250mg injection (Orencia®)
For use in line with NICE TA373 (Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis)
For use in line with NICE TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed) 
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
   
Adalimumab (Humira®)
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Formulary
NICE Formulary
High Cost Medicine

Adalimumab 20mg pre filled syringes

Adalimumab 40mg injection
Adalimumab 40mg pre-filled pen
For use in line with NICE TA373 (Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis)
For use in line with NICE TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed)
For use in line with NICE TA392 (Adalimumab for treating moderate to severe hidradenitis suppurativa)
For use in line with NICE TA199 (Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis)

 
Link  NICE TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA392: Adalimumab for treating moderate to severe hidradenitis suppurativa
   
Cytotoxic Drug Azathioprine
(rheumatology)
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Formulary
On Formulary
See section 8.2.1 
   
Belimumab (Benlysta®)
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Formulary
NICE Formulary
Belimumab 120mg powder concentrate for infusion (Benlysta®)
Belimumab 400mg powder concentrate for infusion (Benlysta®)
For use in line with NICE TA397 (Belimumab for treating active autoantibody-positive systemic lupus erythematosus)
Belimumab will be commissioned by NHS England from agreed Trusts only. The agreed list of Trusts does NOT include CWHT. 
Link  NICE TA397: Belimumab for treating active autoantibody-positive systemic lupus erythematosus
   
Certolizumab Pegol (Cimzia®)
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Formulary
NICE Formulary
High Cost Medicine

Certolizumab Pegol 200mg/ml pre-filled injection(Cimzia®)
Certolizumab Pegol 200mg/ml pre-filled pen(AutoClicks®)(Cimzia®)

For use in line with NICE TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed)
For use in line with NICE TA186 (Certolizumab pegol for the treatment of rheumatoid arthritis)
For use in line with NICE TA415 (Certolizumab pegol for treating rheumatoid arthritis after inadequate response to a TNF-alpha inhibitor)
For use line with NICE TA445 (Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs)

For use in line with NICE TA574 - Certolizumab pegol for treating moderate to severe plaque psoriasis 

 
Link  NICE TA186: Certolizumab pegol for the treatment of rheumatoid arthritis
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA415: Certolizumab pegol for treating rheumatoid arthritis after inadequate response to a TNF-alpha inhibitor
Link  NICE TA445: Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs
   
Ciclosporin
(Rhematology)
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Formulary
On Formulary
See section 8.2.2 
   
Etanercept (Benepali®)
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Formulary
On Formulary
Etanercept 50mg solution in pre-filled pen (Benepali®)
Etanercept 50mg solution in pre-filled syringe (Benepali®) 
   
Etanercept (Enbrel®)
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Formulary
NICE Formulary
High Cost Medicine
Etanercept 25mg injection (Enbrel®)
Etanercept 50mg pre-filled syringe (Enbrel®)
For use in line with NICE TA373 (Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis)
For use in line with NICE TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed) 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis - etanercept, infliximab and adalimumab
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
   
Golimumab (Simponi®)
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Formulary
NICE Formulary
High Cost Medicine

Golimumab 50mg injection (Simponi®)
For use in line with NICE TA220 (Golimumab for the treatment of psoriatic arthritis)
For use in line with NICE TA225 (Golimumab for the treatment of rheumatoid arthritis after the failure of previous disease-modifying anti-rheumatic drugs)
For use in line with NICE TA233 (Golimumab for the treatment of ankylosing spondylitis)
For use in line with NICE TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed)

For use in line with NICE TA497 - Golimumab for treating non-radiographic axial spondyloarthritis

 
Link  NICE TA220: Psoriatic arthritis - golimumab
Link  NICE TA225: Rheumatoid arthritis - golimumab
Link  NICE TA233: Ankylosing spondylitis - golimumab
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
   
Infliximab (Remicade®)
(For use in line with NICE guidance)
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Formulary
On Formulary
High Cost Medicine
Infliximab 50mg injection (Remicade®)
Infliximab 100mg injection (Remicade®)
For use in line with NICE TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed)
For use in line with NICE TA199 (Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis)
 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis - etanercept, infliximab and adalimumab
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
   
Leflunomide
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Formulary
On Formulary
Leflunomide 10mg tablet
Leflunomide 20mg tabet
Leflunomide 100mg tablet 
   
Cytotoxic Drug Methotrexate
(rheumatology)
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Formulary
On Formulary
Methotrexate 2.5mg tablet
Methotrexate 10mg tablet
Methotrexate injections 
Link  UKMI Q&A: Methotrexate and alcohol guidance
   
Rituximab (MabThera®)
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Formulary
NICE Formulary
High Cost Medicine
Rituximab 10mg/ml injection (MabThera®)
For use in line with NICE TA195 (Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor)

For use in line with NICE TA308 (Rituximab in combination with glucocorticoids for treating anti-neutrophil cytoplasmic antibody-associated vasculitis)
 
Link  NICE TA195: Rheumatoid arthritis - drugs for treatment after failure of a TNF inhibitor
Link  NICE TA308: Rituximab in combination with glucocorticoids for treating anti-neutrophil cytoplasmic antibody-associated vasculitis
   
Tocilizumab (RoActemra®)
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Formulary
NICE Formulary
High Cost Medicine

Tocilizumab 20mg/ml IV infusion - 4ml (80mg) (RoActemra®)
Tocilizumab 20mg/ml IV infusion - 10ml (200mg) (RoActemra®)
Tocilizumab 20mg/ml IV infusion - 20ml (400mg) (RoActemra®)
Tocilizumab 162mg pre-filled syringe (RoActemra®)
For use in line with NICE TA238 (Tocilizumab for the treatment of systemic juvenile idiopathic arthritis)
For use in line with NICE TA247 (Tocilizumab for the treatment of rheumatoid arthritis)
For use in line with NICE TA373 (Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis)
For use in line with NICE guidance TA375 (Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed)

 
Link  NICE TA238: Arthritis (juvenile idiopathic, systemic) - tocilizumab
Link  NICE TA247: Rheumatoid arthritis - tocilizumab (rapid review TA198)
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
   
10.01.03  Expand sub section  Sulfasalazine
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

On Formulary

Formulary  

NICE Formulary

Nice Approved / Formulary  

NICE Approved

NICE approved  

Amber Restricted

Amber Restricted Use  

Non Formulary

Non Formulary  

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