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 Formulary Chapter 13: Skin - Full Chapter
13.05.03  Expand sub section  Drugs affecting the immune response
Adalimumab (Humira®)
(Dermatology)
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Formulary
NICE Formulary
High Cost Medicine
see section 10.1
For use in line with NICE TA455 (Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people) 
Link  NICE TA146: Psoriasis - adalimumab
Link  NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
   
Apremilast (Otezla®)
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Formulary
NICE Formulary
Apremilast (Otezla®) 10mg film coated tablets
Apremilast (Otezla®) 20mg film coated tablets
Apremilast (Otezla®) 30mg film coated tablets
For use in line with NICE TA419 (Apremilast for treating moderate to severe plaque psoriasis)

For use in line with NICE TA433 (Apremilast for treating active psoriatic arthritis)
 
Link  NICE TA419: Apremilast for treating moderate to severe plaque psoriasis
Link  NICE TA433: Apremilast for treating active psoriatic arthritis
   
Cytotoxic Drug Azathioprine
(Dermatology)
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Formulary
On Formulary
see section 8.2 
Link  UKMI Q&A: Can mothers breastfeed while taking azathioprine?
   
Brodalumab (Kyntheum®)
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Formulary
NICE Formulary
High Cost Medicine

Brodalumab (Kyntheum®) 210mg solution for injection

 

For use in line with NICE TA511 - Brodalumab for treating moderate to severe plaque psoriasis

 
   
Ciclosporin
(Dermatology)
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Formulary
On Formulary
see section 8.2 
   
Dupilumab (Dupixent®)
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Formulary
NICE Formulary
High Cost Medicine
NHS England

Dupilumab (Dupixent®) 300mg pre-filled syringe

To be used in line with NICE TA534 (Dupilumab for treating moderate to severe atopic dermatitis)

 
   
Etanercept (Enbrel®)
(Dermatology)
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Formulary
NICE Formulary
High Cost Medicine
see section 10.1
For use in line with NICE TA103: Etanercept and efalizumab for the treatment of adults with psoriasis
For use in line with NICE TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis
For use in line with NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
 
Link  NICE TA103: Psoriasis - efalizumab and etanercept
Link  NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
   
Guselkumab (Tremfya®)
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Formulary
NICE Formulary
High Cost Medicine
NHS England

Guselkumab (Tremfya®) 100mg solution for injection

For use in line with NICE TA521 (Guselkumab for treating moderate to severe plaque psoriasis)

 
   
Infliximab (Remicade®)
(Dermatology)
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Formulary
NICE Formulary
High Cost Medicine
see section 10.1
For use in line with NICE TA134: Infliximab for the treatment of adults with psoriasis 
Link  NICE TA134: Infliximab for psoriasis
   
Ixekizumab  (Taltz®)
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Formulary
NICE Formulary
Ixekizumab (Taltz®)80mg solution for injection
For use in line with NICE TA442 (Ixekizumab for treating moderate to severe plaque psoriasis) 
Link  NICE TA442: Ixekizumab for treating moderate to severe plaque psoriasis
   
Cytotoxic Drug Methotrexate
(Dermatology)
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Formulary
On Formulary
see section 10.1 
Link  UKMI Q&A: What is the clinical significance of the interaction between methotrexate and penicillins? (Oct13)
   
Pimecrolimus (Elidel®)
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Formulary
NICE Formulary
Pimecrolimus (Elidel®) 1% cream
For use in line with NICE TA82: Tacrolimus and pimecrolimus for atopic eczema 
Link  NICE TA82: Pimecrolimus and tacrolimus for atopic dermatitis (eczema)
   
Secukinumab (Cosentyx®)
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Formulary
NICE Formulary
High Cost Medicine
Secukinumab (Cosentyx®) 150mg prefilled pen
For use in line with NICE TA350 (Secukinumab for treating moderate to severe plaque psoriasis)
For use in line with NICE TA407 (Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitors)
 
Link  NICE TA350: Secukinumab for treating moderate to severe plaque psoriasis
Link  NICE TA407: Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitors
   
Tacrolimus (Protopic®)
(Only FY2 and above may prescribe)
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Formulary
NICE Formulary
Tacrolimus (Protopic®) 0.03% ointment
Tacrolimus (Protopic®) 0.1% ointment
Tacrolimus 0.1% in orabase
For use in line with NICE TA82: Tacrolimus and pimecrolimus for atopic eczema 
Link  NICE TA82: Pimecrolimus and tacrolimus for atopic dermatitis (eczema)
   
Ustekinumab (Stelara®)
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Formulary
NICE Formulary
High Cost Medicine
Ustekinumab (Stelara®) 45mg/0.5ml injection
For use in line with NICE TA180 (Ustekinumab for the treatment of adults with moderate to severe psoriasis)
For use in line with NICE TA340 (Ustekinumab for treating active psoriatic arthritis)
For use in line with NICE TA455 (Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people)

For use in line with NICE TA456 (Ustekinumab for moderately to severely active Crohn’s disease after previous treatment) 
Link  NICE TA: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
Link  NICE TA180: Psoriasis - ustekinumab
Link  NICE TA340: Ustekinumab for treating active psoriatic arthritis
Link  NICE TA456: Ustekinumab for moderately to severely active Crohn’s disease after previous treatment
   
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

On Formulary

Formulary  

NICE Formulary

Nice Approved / Formulary  

NICE Approved

NICE approved  

Amber Restricted

Amber Restricted Use  

Non Formulary

Non Formulary  

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