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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.01  Positive inotropic drugs
02.01.01  Cardiac glycosides
Digoxin
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Formulary
On Formulary
Digoxin 62.5mcg tablet
Digoxin 125mcg tablet
Digoxin 250mcg tablet
Digoxin 50mcg/ml elixir
Digoxin 500mcg/2ml injection
 
   
02.01.01  Digoxin-specific antibody
Digoxin specific antibody fragments (Digifab®)
(Cardiac glycoside (digoxin) toxicity)
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Formulary
On Formulary
High Cost Medicine
Digoxin specific antibody fragments(DigiFab®) 40mg intravenous infusion 
   
02.01.02  Phosphodiesterase type-3 inhibitors
Milrinone (Primacor®)
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Formulary
On Formulary
Milrinone (Primacor®) 1mg/ml injection 
   
02.02  Diuretics to top
02.02.01  Thiazides and related diuretics
Bendroflumethiazide
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Formulary
On Formulary
Bendroflumethiazide 2.5mg tablet
Bendroflumethiazide 5mg tablet 
   
Indapamide
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Formulary
On Formulary
Indapamide 2.5mg tablet
Indapamide 1.5mg SR tablet 
   
Metolazone
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Formulary
On Formulary
Metolazone 5mg tablet 
   
Chlorothiazide
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Unlicensed Drug Unlicensed
On Formulary
Chlorothiazide 250mg/5ml oral solution 
   
02.02.02  Loop diuretics
Bumetanide
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Formulary
On Formulary
Bumetanide 1mg tablet
Bumetanide 5mg tablet
Bumetanide 1mg/5ml liquid 
   
Furosemide
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Formulary
On Formulary
Furosemide 20mg tablet
Furosemide 40mg tablet
Furosemide 500mg tablet
Furosemide 40mg/5ml oral solution (Adult use only)
Furosemide 50mg/5ml oral solution (Paediatric use only)
Furosemide 20mg/2ml injection 
   
02.02.03  Potassium-sparing diuretics and aldosterone antagonists
Amiloride Hydrochloride
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Formulary
On Formulary
Amiloride 5mg tablet
Amiloride 5mg/5ml solution 
   
02.02.03  Aldosterone antagonists
Eplerenone
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Formulary
On Formulary
Eplerenone 25mg tablet
Eplerenone 50mg tablet 
Link  NICE CG108: Chronic heart failure
   
Spironolactone
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Formulary
On Formulary
Spironolactone 25mg tablet
Spironolactone 50mg tablet
Spironolactone 100mg tablet
Spironolactone 50mg/50ml suspension (Unlicensed) 
   
02.02.04  Potassium-sparing diuretics with other diuretics to top
Co-amilofruse
(amiloride/furosemide)
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Formulary
On Formulary
Co-amilofruse 2.5/20 tablet
Co-amilofruse 5/40 tablet 
   
Co-amilozide
(amiloride/hydrochlorothiazide)
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Formulary
On Formulary
Co-amilozide 5/50mg tablet 
   
02.02.05  Osmotic diuretics
Mannitol
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Formulary
On Formulary
Mannitol 10% infusion
Mannitol 20% infusion 
   
02.02.06  Mercurial diuretics
02.02.07  Carbonic anhydrase inhibitors
02.02.08  Diuretics with potassium
02.03  Anti-arrhythmic drugs to top
02.03.01  Management of arrhythmias
02.03.02  Drugs for arrhythmias
02.03.02  Supraventricular arrhythmias
Adenosine
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Formulary
On Formulary
Adenosine 1mg/ml injection (unlicensed) - for WMUH use only
Adenosine 3mg/ml injection (2ml vial)
Adenosine 3mg/ml injection (10ml vial) 
   
Dronedarone
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Formulary
NICE Formulary
Dronedarone 400mg tablet
For use in line with NICE TA197 (Dronedarone for the treatment of non-permanent atrial fibrillation) 
Link  NICE TA197: Atrial fibrillation - dronedarone
   
02.03.02  Supraventricular and ventricular arrhythmias
Amiodarone
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Formulary
On Formulary
Amiodarone 100mg tablet
Amiodarone 200mg tablet
Amiodarone 150mg/3ml injection
Amiodarone 300/10ml pre-filled injection 
   
Disopyramide
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Formulary
On Formulary
Disopyramide 100mg capsule
Disopyramide 150mg capsule 
   
Flecainide
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Formulary
On Formulary

Flecainide 50mg tablet

Flecainide 100mg tablet


Flecainide 10mg/ml injection (Tambocor®)

 
   
Propafenone
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Formulary
On Formulary
Propafenone 300mg tablet 
   
02.03.02  Ventricular arrhythmias to top
Lidocaine
(Cardiac)
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Formulary
On Formulary
Lidocaine 0.5% (5mg/ml) injection (10ml ampoule)
Lidocaine 1% (10mg/ml) MiniJet® injection
Lidocaine 1% (10mg/ml) injection (2ml ampoule)
Lidocaine 1% (10mg/ml) injection (5ml ampoule)
Lidocaine 1% (10mg/ml) injection (20ml ampoule)
Lidocaine 2% (20mg/ml) injection (2ml ampoule)
Lidocaine 2% (20mg/ml) injection (5ml ampoule)
Lidocaine 2% (20mg/ml) injection (20ml ampoule)
Lidocaine 0.2% in glucose 5% infusion (500ml bag) 
   
02.04  Beta-adrenoceptor blocking drugs
Atenolol
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Formulary
On Formulary
Atenolol 25mg tablet
Atenolol 50mg tablet
Atenolol 100mg tablet
Atenolol 25mg/5ml syrup 
   
Bisoprolol
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Formulary
On Formulary
Bisoprolol 1.25mg tablet
Bisoprolol 2.5mg tablet
Bisoprolol 5mg tablet 
   
Carvedilol
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Formulary
On Formulary
Carvedilol 3.125mg tablet
Carvedilol 6.25mg tablet
Carvedilol 12.5mg tablet
Carvedilol 25mg tablet
 
   
Co-tenidone
(atenolol and chlortalidone)
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Formulary
On Formulary
Co-tenidone 100/25 tablet 
   
Esmolol
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Formulary
On Formulary
Esmolol 10mg/ml injection (250ml infusion bag) 
   
Labetalol
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Formulary
On Formulary
Labetalol 50mg tablet
Labetalol 100mg tablet
Labetalol 200mg tablet
Labetalol 100mg/20ml injection 
   
Metoprolol
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Formulary
On Formulary
Metoprolol 50mg tablet
Metoprolol 1mg/ml injection (Betaloc®) 
   
Nebivolol
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Formulary
On Formulary
Nebivolol 5mg tablet 
   
Propranolol
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Formulary
On Formulary
Propranolol 10mg tablet
Propranolol 40mg tablet
Propranolol 80mg SR capsule
Propranolol 1mg/ml oral solution
Propranolol 1mg/ml injection 
   
Sotalol
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Formulary
On Formulary
Sotalol 40mg tablet
Sotalol 80mg tablet 
   
02.05  Drugs affecting the renin-angiotensin system and some other antihypertensive drugs
02.05.01  Vasodilator antihypertensive drugs
Hydralazine
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Formulary
On Formulary
Hydralazine 25mg tablet
Hydralazine 20mg injection 
   
Minoxidil (Loniten®)
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Formulary
On Formulary
Minoxidil (Loniten®) 2.5mg tablet
Minoxidil (Loniten®) 5mg tablet
Minoxidil (Loniten®) 10mg tablet 
   
Sildenafil
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Formulary
On Formulary
High Cost Medicine
Sildenafil 20mg tablet
Sildenafil 25mg/5ml SF oral liquid 
   
Sodium Nitroprusside
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Formulary
On Formulary
Sodium Nitroprusside 50mg/5ml injection 
   
02.05.02  Centrally acting antihypertensive drugs
Clonidine
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Formulary
On Formulary

Clonidine 25mcg tablet
Clonidine 100mcg tablet
Clonidine 150mcg/ml injection

Clonidine 50mcg/5ml oral solution

 
   
Methyldopa
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Formulary
On Formulary
Methyldopa 125mg tablet
Methyldopa 250mg tablet 
   
Moxonidine
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Formulary
On Formulary
Moxonidine 200mcg tablet
Moxonidine 300mcg tablet
Moxonidine 400mcg tablet 
   
02.05.03  Adrenergic neurone blocking drugs to top
Guanethidine Monosulphate
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Formulary
On Formulary
Guanethidine 10mg/ml injection 
   
02.05.04  Alpha-adrenoceptor blocking drugs
Doxazosin
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Formulary
On Formulary
Doxazosin 1mg tablet
Doxazosin 2mg tablet
Doxazosin 4mg tablet
Doxazosin 4mg MR tablet 
Link  UKMI Q&A: How should conversion between doxazosin formulations be carried out?
   
Indoramin
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Formulary
On Formulary
Indoramin 20mg tablet 
   
Prazosin
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Formulary
On Formulary
Prazosin 500mcg tablet 
   
Terazosin
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Formulary
On Formulary
Terazosin 2mg tablet
Terazosin 5mg tablet 
   
02.05.04  Phaeochromocytoma
Phenoxybenzamine Hydrochloride
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Formulary
On Formulary
Phenoxybenzamine 10mg capsule
 
   
Phentolamine
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Formulary
On Formulary
Phentolamine 10mg/ml injection 
   
02.05.05  Drugs affecting the renin-angiotensin system
02.05.05  Heart Failure
Sacubitril valsartan (Entresto®)
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Formulary
NICE Formulary
Sacubitril valsartan 24mg/26mg film coated tablet (Entresto®)
Sacubitril valsartan 49mg/51mg film coated tablet (Entresto®)
Sacubitril valsartan 97mg/103mg film coated tablet (Entresto®)
For use in line with NICE guidance TA 388 (Sacubitril valsartan for treating symptomatic chronic heart failure with reduced ejection fraction)
 
Link  NICE TA388: Sacubitril valsartan for treating symptomatic chronic heart failure with reduced ejection fraction
   
02.05.05.01  Angiotensin-converting enzyme inhibitors (ACE inhibitors) to top
Captopril
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Formulary
On Formulary

Captopril 12.5mg tablet
Captopril 25mg tablet

Captopril 50mg tablet

Captopril 8mg/5ml oral liquid

 
   
Enalapril
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Formulary
On Formulary
Enalapril 2.5mg tablet
Enalapril 5mg tablet
Enalapril 10mg tablet
Enalapril 20mg tablet 
   
Lisinopril
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Formulary
On Formulary
Lisinopril 2.5mg tablet
Lisinopril 5mg tablet
Lisinopril 10mg tablet
Lisinopril 20mg tablet 
   
Perindopril
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Formulary
On Formulary
Perindopril 2mg tablet
Perindopril 4mg tablet
Perindopril 8mg tablet 
   
Ramipril
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Formulary
On Formulary
Ramipril 1.25mg capsule
Ramipril 2.5mg capsule
Ramipril 5mg capsule
Ramipril 10mg capsule
 
   
02.05.05.02  Angiotensin-II receptor antagonists
Candesartan
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Formulary
On Formulary

Candesartan 2mg tablet
Candesartan 4mg tablet
Candesartan 8mg tablet
Candesartan 16mg tablet

Candesartan 32 mg tablet

 
   
Irbesartan
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Formulary
On Formulary
Irbesartan 75mg tablet
Irbesartan 150mg tablet
Irbesartan 300mg tablet 
   
Losartan
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Formulary
On Formulary
Losartan 25mg tablet
Losartan 50mg tablet
Losartan 100mg tablet 
   
Valsartan
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Formulary
On Formulary
Valsartan 40mg tablet
Valsartan 80mg capsule
Valsartan 160mg capsule 
   
02.05.05.03  Renin inhibitors
Aliskiren
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Formulary
On Formulary
Aliskiren 150mg tablet
Aliskiren 300mg tablet 
   
02.06  Nitrates, calcium-channel blockers, and potassium-channel activators
02.06  Angina
02.06.01  Nitrates to top
Glyceryl Trinitrate
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Formulary
On Formulary
Glyceryl Trinitrate 400mcg SL spray
Glyceryl Trinitrate 500mcg SL tablet
Glyceryl Trinitrate 5mg/24 hours patch
Glyceryl Trinitrate 10mg/24 hours patch
Glyceryl Trinitrate 50mg/10ml injection 
   
Isosorbide Dinitrate
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Formulary
On Formulary
Isosorbide dinitrate 10mg tablet
Isosorbide dinitrate 20mg tablet
Isosorbide dinitrate 0.5mg/ml injection
Isosorbide dinitrate 1mg/ml injection 
   
Isosorbide Mononitrate
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Formulary
On Formulary
Isosorbide mononitrate 10mg tablet
Isosorbide mononitrate 20mg tablet
Isosorbide mononitrate 25mg MR capsule
Isosorbide mononitrate 50mg MR capsule
Isosorbide mononitrate 60mg MR tablet 
   
02.06.02  Calcium-channel blockers
Amlodipine
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Formulary
On Formulary
Amlodipine 5mg tablet
Amlodipine 10mg tablet 
   
Diltiazem
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Formulary
On Formulary
Diltiazem (Non-proprietary) 60mg MR tablet
Diltiazem (Adizem-SR®) 90mg capsule
Diltiazem (Adizem-SR®) 120mg capsule
Diltiazem (Adizem-SR®) 180mg capsule
Diltiazem (Adizem-SR®) 120mg tablet
Diltiazem (Adizem-XL®) 120mg capsule
Diltiazem (Adizem-XL®) 180mg capsule
Diltiazem (Adizem-XL®) 200mg capsule
Diltiazem (Adizem-XL®) 240mg capsule
Diltiazem (Adizem-XL®) 300mg capsule
Diltiazem (Tildiem LA®) 200mg capsule
Diltiazem (Tildiem LA®) 300mg capsule
Diltiazem (Tildiem Retard®) 90mg tablet
Diltiazem (Tildiem Retard®) 120mg tablet
Diltiazem (Slozem®) 120mg capsule
Diltiazem (Slozem®) 180mg capsule
Diltiazem (Slozem®) 240mg capsule
Diltiazem (Slozem®) 300mg capsule
 
   
Felodipine
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Formulary
On Formulary
Felodipine 2.5mg SR tablets
Felodipine 5mg SR tablets
Felodipine 10mg SR tablets
 
   
Nifedipine
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Formulary

Nifedipine (Adalat LA®) 20mg tablet
Nifedipine (Adalat LA®) 30mg tablet
Nifedipine (Adalat LA®) 60mg tablet

Nifedipine (Adalat Retard®) 20mg tablet


Nifedipine (Non-proprietary) 5mg capsule
Nifedipine (Non-proprietary) 10mg capsule


Nifedipine (Coracten SR®) 10mg capsule
Nifedipine (Coracten SR®) 20mg capsule

Nifedipine (Nifedipress MR®) 10mg tablets

 
   
Nimodipine (Nimotop®)
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Formulary
On Formulary
Nimodipine (Nimotop®)30mg tablet
Nimodipine (Nimotop®) 200mcg/ml injection (50ml vial) 
   
Verapamil
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Formulary
On Formulary
Verapamil 40mg tablet
Verapamil 80mg tablet
Verapamil 120mg SR tablet
Verapamil 240mg SR tablet
Verapamil 5mg/2ml injection (Securon®) 
Link  UKMI Q&A: Evidence for verapamil for cluster headache
   
02.06.03  Other anitanginal drugs
Ivabradine (Procoralan®)
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Formulary
On Formulary
Ivabradine 5mg tablet (Procoralan®)
Ivabradine 7.5mg tablet (Procoralan®)
For use in line with NICE TA267 (Ivabradine for treating chronic heart failure)
 
Link  NICE Guidelines GC126: Stable angina: management
Link  NICE TA267: Ivabradine for treating chronic heart failure
   
Nicorandil
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Formulary
On Formulary
Nicorandil 10mg tablet
Nicorandil 20mg tablet 
   
Ranolazine (Ranexa®)
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Formulary
On Formulary
Ranolazine 375mg MR tablet (Ranexa®)
Ranolazine 500mg MR tablet (Ranexa®)
Ranolazine 750mg MR tablet (Ranexa®) 
Link  NICE CG126: Guidance on Stable Angina
   
02.06.04  Peripheral vasodilators and related drugs
Naftidrofuryl
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Formulary
On Formulary
Naftidrofuryl 100mg capsule
For use in line with NICE TA223 (Cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease) 
Link  NICE TA223: Cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease
   
02.06.04  Other preparations used in peripheral vascular disease
02.07  Sympathomimetics to top
Levosimendan
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Unlicensed Drug Unlicensed
On Formulary
Levosimendan 2.5mg/ml infusion 
   
02.07.01  Inotropic sympathomimetics
Dobutamine
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Formulary
On Formulary
Dobutamine 250mg/20ml amps 
   
Dopamine
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Formulary
On Formulary
Dopamine 40mg/1ml injection  
   
Dopexamine
(Dopacard®)
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Formulary
On Formulary
Dopexamine 50mg/5ml injection (Dopacard®) 
   
02.07.02  Vasoconstrictor sympathomimetics
Ephedrine
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Formulary
On Formulary
Ephedrine hydrochloride 30mg/ml injection 
   
Metaraminol
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Formulary
On Formulary
Metaraminol 10mg/ml injection 
   
Noradrenaline / Norepinephrine
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Formulary
On Formulary
Noradrenaline 1mg/1ml Injection (4ml amps)
 
   
Phenylephrine
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Formulary
On Formulary
Phenylephrine hydrochloride 10mg/ml injection 
   
02.07.03  Cardiopulmonary resuscitation
Adrenaline / Epinephrine
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Formulary
On Formulary
Adrenaline 1:1000 injection
Adrenaline 1:10000 injection
Adrenaline 1:10000 Mini-I-Jet injection 
   
02.08  Anticoagulants and protamine
Idarucizumab (Praxbind®)
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Formulary
On Formulary
Idarucizumab (Praxbind®) 2.5g/50ml solution for injection 
   
02.08.01  Parenteral anticoagulants to top
Argatroban (Exembol®)
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Formulary
On Formulary
Argatroban (Exembol®) 100mg/1ml injection 
   
02.08.01  Heparin
Heparin
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Formulary
On Formulary
Heparin 100units/ml injection
Heparin 1000units/ml injection
Heparin 5000units/5ml injection
Heparin (Hepsal) 50units/5ml injection
Heparin Calcium syringe
 
   
02.08.01  Low molecular weight heparins
Dalteparin (Fragmin®)
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Formulary
On Formulary
Dalteparin (Fragmin®) 2500unit/0.2ml syringe
Dalteparin (Fragmin®) 5000unit/0.2ml syringe
Dalteparin (Fragmin®) 10000unit/0.4ml syringe
Dalteparin (Fragmin®) 12500unit/0.5ml syringe
Dalteparin (Fragmin®) 10000unit/1ml syringe  
   
Enoxaparin (Clexane®)
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Formulary
On Formulary
Enoxaparin (Clexane®) 20mg/0.2ml syringe
Enoxaparin (Clexane®) 40mg/0.4ml syringe
Enoxaparin (Clexane®) 60mg/0.6ml syringe
Enoxaparin (Clexane®) 80mg/0.8ml syringe
Enoxaparin (Clexane®) 100mg/1ml syringe
Enoxaparin (Clexane® Forte) 120mg/0.8ml syringe
Enoxaparin (Clexane® Forte) 150mg/1ml syringe
 
   
02.08.01  Heparinoids
Danaparoid (Orgaran®)
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Formulary
On Formulary
Danaparoid (Orgaran®) 750units/0.6ml injection 
   
02.08.01  Hirudins
Epoprostenol (Veletri®)
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Formulary
On Formulary
Epoprostenol (Veletri®) 500mcg pwoder for infusion  
   
02.08.01  Fondaparinux to top
Fondaparinux (Arixtra®)
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Formulary
On Formulary
Fondaparinux 2.5mg injection
 
   
02.08.02  Oral anticoagulants
Acenocoumarol (Sinthrome®)
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Formulary
On Formulary
Acenocoumarol (Sinthrome®) 1mg tablets  
   
Apixaban (Eliquis®)
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Formulary
NICE Formulary
Apixaban (Eliquis®) 2.5mg tablet
Apixaban (Eliquis®) 5mg tablet
For use in line with NICE TA245 (Apixaban for the prevention of venous thromboembolism after total hip or knee replacement in adults)
For use in line with NICE TA275 (Apixaban for preventing stroke and systemic embolism in people with nonvalvular atrial fibrillation)
For use in line with NICE TA341 (Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism) 
Link  NICE TA245: Venous thromboembolism - apixaban (hip and knee surgery
Link  NICE TA275: Stroke and systemic embolism (prevention, non-valvular atrial fibrillation) - apixaban
Link  NICE TA341: Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism
   
Dabigatran (Pradaxa®)
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Formulary
NICE Formulary
Dabigatran (Pradaxa®) 75mg capsule
Dabigatran (Pradaxa®) 110mg capsule
Dabigatran (Pradaxa®) 150mg capsule
For use in line with NICE TA157 (Dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adults)
For use in line with NICE TA249 (Dabigatran for Stroke prevention in AF)
For use in line with NICE TA327 (Dabigatran etexilate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism) 
Link  NICE TA157: Dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adults
Link  NICE TA249: Dabigatran for Stroke prevention in AF
Link  NICE TA327: Dabigatran etexilate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism
   
Edoxaban (Lixiana®)
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Formulary
NICE Formulary
Edoxaban (Lixiana®) 15mg film coated tablet
Edoxaban (Lixiana®) 30mg film coated tablet
Edoxaban (Lixiana®) 60mg film coated tablet
For use in line with NICE TA354 (Edoxaban for treating and for preventing deep vein thrombosis and pulmonary embolism)
For use in line with NICE TA355 (Edoxaban for preventing stroke and systemic embolism in people with non-valvular atrial fibrillation) 
Link  NICE TA354: Edoxaban for treating and for preventing deep vein thrombosis and pulmonary embolism
Link  NICE TA355: Edoxaban for preventing stroke and systemic embolism in people with non-valvular atrial fibrillation
   
Phenindione
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Formulary
On Formulary
Phenindione 10mg tablet
Phenindione 25mg tablet
Phenindione 50mg tablet 
   
Rivaroxaban (Xarelto®)
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Formulary
NICE Formulary
Rivaroxaban (Xarelto®) 2.5mg tablets
Rivaroxaban (Xarelto®) 10mg tablets
Rivaroxaban (Xarelto®) 15mg tablets
Rivaroxaban (Xarelto®) 20mg tablets
For use in line with NICE TA170 (Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adults)
For use in line with NICE TA261 (Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism)
For use in line with NICE TA287 (Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolism)
For use in line with NICE TA335 (Rivaroxaban for preventing adverse outcomes after acute management of acute coronary syndrome)
 
Link  NICE TA170: Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adults
Link  NICE TA261: Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolism
Link  NICE TA287:Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolism
Link  NICE TA335: Rivaroxaban for preventing adverse outcomes after acute management of acute coronary syndrome
   
Warfarin
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Formulary
On Formulary
Warfarin 1mg tablets
Warfarin 3mg tablets
Warfarin 5mg tablets  
Link  UKMI Q&A: IM injections in warfarin patients
Link  UKMI Q&A: Warfarin and PPI interaction
   
02.08.02  Stroke prevention in AF
02.08.02  Atrial Fibrillation
02.08.02  VTE treatment
02.08.02  VTE prophylaxis in hip/knee surgery to top
02.08.03  Protamine sulphate
Protamine Sulphate
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Formulary
On Formulary
Protamine sulphate 50mg/5ml injection  
   
02.09  Antiplatelet drugs
Abciximab (ReoPro®)
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Formulary
On Formulary
Abciximab 2mg/ml injection (ReoPro®) - WMUH site only
For use in line with NICE TA47: Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromes
 
Link  NICE TA47: Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromes
   
Aspirin
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Formulary
On Formulary
Aspirin 75mg dispersible tablet
Aspirin 75mg enteric coated tablet
Aspirin 300mg dispersible tablet
Aspirin 300mg suppository
 
Link  UKMI Q&A: Is there evidence to support the use of EC coated aspirin to reduce GI side effects?
   
Clopidogrel
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Formulary
NICE Formulary
Clopidogrel 75mg tablet
For use in line with NICE TA210 (Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events)
 
Link  NICE TA80: Acute coronary syndromes - clopidogrel
Link  NICE TA210: Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events
   
Dipyridamole
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Formulary
NICE Formulary
Dipyridamole 25mg tablet
Dipyridamole 100mg tablet
Dipyridamole 200g SR capsule
Dipyridamole 50mg/50ml oral liquid
For use in line with NICE TA210 (Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events)
 
Link  NICE TA210: Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events
   
Prasugrel (Efient®)
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Formulary
NICE Formulary
Prasugrel (Efient®) 5mg tablet
Prasugrel (Efient®) 10mg tablet
For use in line with NICE TA 317 (Prasugrel with percutaneous coronary intervention for treating acute coronary syndromes) 
Link  NICE TA317: Prasugrel with percutaneous coronary intervention for treating acute coronary syndromes (review of technology appraisal guidance 182)
   
Ticagrelor (Brilique®)
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Formulary
NICE Formulary
Ticagrelor (Brilique®)60mg tablet
Ticagrelor (Brilique®)90mg tablet
For use in line with NICE TA236 (Ticagrelor for the treatment of acute coronary syndromes)
For use in line with NICE TA420 (Ticagrelor for preventing atherothrombotic events after myocardial infarction)
 
Link  NICE TA236: Ticagrelor for the treatment of acute coronary syndromes
Link  NICE TA420: Ticagrelor for preventing atherothrombotic events after myocardial infarction
   
Tirofiban (Aggrastat®)
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Formulary
NICE Formulary
Tirofiban (Aggrastat®) 250mcg in 1ml solution for infusion
For use in line with NICE TA47 (Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromes)
For use in line with NICE CG94 (Unstable angina and NSTEMI: early management) 
Link  NICE CG94: Unstable angina and NSTEMI: early management
Link  NICE TA47 : Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromes
   
02.10  Stable angina, acute coronary syndromes, and fibrinolysis
02.10.01  Management of stable angina and acute coronary syndromes
02.10.02  Fibrinolytic drugs to top
Alteplase
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Formulary
NICE Formulary
Alteplase Actilyse Cathflo® 2mg injection
Alteplase Actilyse 20mg injection
Alteplase Actilyse 50mg injection
CW Site: For use in line with NICE TA264: Alteplase for treating acute ischaemic stroke
WM Site: For use in pulmonary embolism only 
Link  NICE TA264: Alteplase for treating acute ischaemic stroke
   
Streptokinase
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Formulary
On Formulary
Streptokinase 250,000unit injection
Streptokinase 1.5MU injection 
   
Tenecteplase (Metalyse®)
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Formulary
On Formulary
Tenecteplase 10,000unit injection 
   
Urokinase
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Unlicensed Drug Unlicensed
Amber Restricted
Restricted Use: Unlicensed use for catheter blockage
Urokinase 10,000unit injection 
   
02.11  Antifibrinolytic drugs and haemostatics
Tranexamic Acid
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Formulary Tranexamic acid 500mg tablet
Tranexamic acid (SF) 500mg/5ml suspension
Tranexamic acid 500mg/5ml injection 
   
02.11  Blood-related products
Drotrecogin Alfa (Activated) (Xigris®)
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Formulary
NICE Formulary
Drotrecogin Alfa (Activated) infusion
For use in line with NICE TA84: Drotrecogin alfa (activated) for severe sepsis 
Link  NICE TA84: Drotrecogin alfa (activated) for severe sepsis
   
Factor IX Fraction, Dried
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Formulary
On Formulary
High Cost Medicine
Factor IX Fraction, Dried (Benefix®)
Factor IX Fraction, Dried (Alphanine®) 
   
Factor VIII Fraction, Dried
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Formulary
On Formulary
High Cost Medicine
Factor VIII Fraction, Dried (Advate®)
Factor VIII Fraction, Dried (Haemate®)
Factor VIII Fraction, Dried (Helixate®)
Factor VIII Fraction, Dried (Kogenate®) 
   
Factor XI
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Formulary
On Formulary
High Cost Medicine
Factor XI 
   
Factor XII
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Formulary
High Cost Medicine
Factor XII 
   
Fresh Frozen Plasma
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Formulary
On Formulary
Fresh frozen plasma 
   
Protein C Concentrate (Ceprotin®)
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Formulary
On Formulary
High Cost Medicine
Protein C Concentrate (Ceptoprin®) 
   
Prothrombin Complex Concentrate  (Octaplex®)
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Formulary
On Formulary
High Cost Medicine
Prothrombin Complex Concentrate (Octaplex®) 
   
02.12  Lipid-regulating drugs
Alirocumab (Praluent®)
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Formulary
NICE Formulary
Alirocumab (Praluent®) 75mg solution for injection in pre-filled pen
Alirocumab (Praluent®) 150mg solution for injection in pre-filled pen
Alirocumab (Praluent®) 75mg solution for injection in pre-filled syringe
Alirocumab (Praluent®) 150mg solution for injection in pre-filled syringe
For use in line with NICE TA393 (Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia) 
Link  NICE TA393: Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
   
Evolocumab (Repatha®)
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Formulary
NICE Formulary
Evolocumab (Repatha SureClick®) 140mg solution for injection in pre-filled syringe
Evolocumab (Repatha SureClick®) 140mg solution for injection in pre-filled pen
Evolocumab (Repatha SureClick®) 420mg solution for injection in cartridge
For use in line with NICE TA 394 (Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia) 
Link  NICE TA394: Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
   
02.12  Bile acid sequestrants
Colesevelam (Cholestagel®)
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Formulary Colesevelam 625g film coated tablet 
   
Colestyramine
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Formulary
On Formulary
Colestyramine (Questran Light®) 4g sachet
Colestyramine 4g sugarfree sachet
 
   
02.12  Ezetimibe to top
Ezetimibe (Ezetrol®)
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Formulary
NICE Formulary
Ezetimibe 10mg tablet
For use in line with NICE TA385 (Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemia) 
Link  NICE TA385: Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemia
   
02.12  Fibrates
Bezafibrate
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Formulary
On Formulary
Bezafibrate 400mg MR tablet 
   
Fenofibrate
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Formulary
On Formulary
Fenofibrate 160mg micronised tablet
Fenofibrate micronised 267mg capsule
Fenofibrate micronised 200mg capsule 
   
Gemfibrozil
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Formulary
On Formulary
Gemfibrozil 300mg capsule 
   
02.12  Statins
Atorvastatin
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Formulary
On Formulary
Atorvastatin 10mg tablet
Atorvastatin 20mg tablet
Atorvastatin 40mg tablet 
   
Fluvastatin
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Formulary
On Formulary
Fluvastatin 20mg capsule
Fluvastatin 40mg capsule
Fluvastatin 80mg MR tablet  
   
Pravastatin
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Formulary
On Formulary
Pravastatin 10mg tablet
Pravastatin 20mg tablet
Pravastatin 40mg tablet 
   
Rosuvastatin
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Formulary
On Formulary
Rosuvastatin 5mg tablet
Rosuvastatin 10mg tablet
Rosuvastatin 20mg tablet
Rosuvastatin 40mg tablet 
   
Simvastatin
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Formulary
On Formulary
Simvastatin 10mg tablet
Simvastatin 20mg tablet
Simvastatin 40mg tablet 
   
02.12  Nicotinic acid group
02.12  Omega-3 fatty acid compounds
02.13  Local sclerosants to top
Ethanolamine Oleate
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Formulary
On Formulary
Ethanolamine Oleate 5% injection 
   
Sclerovein
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Formulary
On Formulary
Sclerovein 1% injection 
   
 ....
 Non Formulary Items
Diazoxide  (Eudemine®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

On Formulary

Formulary  

NICE Formulary

Nice Approved / Formulary  

NICE Approved

NICE approved  

Amber Restricted

Amber Restricted Use  

Non Formulary

Non Formulary  

netFormulary