| Formulary Chapter 5: Infections - Full Chapter
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| 05.01 |
Antibacterial drugs |
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| 05.01 |
Table 1. Summary of antibacterial therapy |
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| 05.01 |
Table 2. Summary of antibacterial prophylaxis |
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| 05.01.01.01 |
Benzylpenicillin and phenoxymethylpenicillin |
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Benzylpenicillin
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Formulary
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Benzylpenicillin 600mg injection
Benzylpenicillin 1.2g injection
Benzylpenicillin 2.4 mega unit
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Phenoxymethylpenicillin
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Formulary
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| 05.01.01.02 |
Penicillinase-resistant penicillins |
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Flucloxacillin
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Formulary
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Flucloxacillin 250mg capsule
Flucloxacillin 500mg capsule
Flucloxacillin 125mg/5ml oral suspension
Flucloxacillin 250mg/5ml oral suspension
Flucloxacillin 250mg injection
Flucloxacillin 500mg injection
Flucloxacillin 1000mg injection
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 UKMI Q&A: Can 2g flucloxacillin be given as a slow IV
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Temocillin (Negaban®)
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Formulary
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Temocillin 1g injection
As per local guideline
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| 05.01.01.03 |
Broad-spectrum penicillins |
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Amoxicillin
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Formulary
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Amoxicillin 250mg capsule
Amoxicillin 500mg capsule
Amoxicillin 125mg/5ml oral liquid
Amoxicillin 250mg/5ml suspension SF
Amoxicillin 3g sachet SF
Amoxicillin 250mg injection
Amoxicillin 500mg injection
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Co-Amoxiclav
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Formulary
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Co-amoxiclav 375mg tablet
Co-amoxiclav 625mg tablet
Co-amoxiclav 125/31mg/5ml SF suspension
Co-amoxiclav 250/62mg/5ml SF suspension
Co-amoxiclav 400/57mg/5ml suspension
Co-amoxiclav 600mg injection
Co-amoxiclav 1.2g injection
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| 05.01.01.04 |
Antipseudomonal penicillins |
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Piperacillin and Tazobactam
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Formulary
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Piperacillin with tazobactam 2.25g injection
Piperacillin with tazobactam 4.5g injection
As per local guideline
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Ticarcillin with clavulanic acid (Timentin®)
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Formulary
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Ticarcillin with clavulanic acid 3.2g injection
Micro only/restricted use
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Pivmecillinam (Selexid®)
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Formulary
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Pivmecillinam 200mg tablet
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| 05.01.02 |
Cephalosporins, carbapenems and other beta-lactums |
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Cefepime (Renapime®)
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Formulary
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Cefepime (Renapime®) 2g solution for injection/infusion
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| 05.01.02 |
Other beta-lactam antibiotics |
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Ceftazidime/Avibactam (Zavicefta®)
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Formulary
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Ceftazidime 2g/Avibactam 0.5g injection (Zavicefta®)
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Imipenem with Cilastatin
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Formulary
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Imipenem with Cilastatin 500mg injection
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| 05.01.02.01 |
Cephalosporins |
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Cefalexin
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Formulary
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Cefalexin 250mg tablet/capsule
Cefalexin 500mg tablet/capsule
Cefalexin 125mg/5ml suspension
Cefalexin 250mg/5ml suspension
AS per local guideline
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Cefixime (Suprax®)
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Formulary
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Cefixime 200mg tablet
As per local guideline
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Cefotaxime
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Formulary
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Cefotaxime 500mg injection
Cefotaxime 1g injection
Cefotaxime 2g injection
As per local guideline
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Ceftazidime
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Formulary
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Ceftazidime 250mg injection
Ceftazidime 500mg injection
Ceftazidime 1g injection
As per local guideline
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Ceftriaxone
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Formulary
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Ceftriaxone 250mg injection
Ceftriaxone 1g injection
Ceftriaxone 2g injection
As per local guideline
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Cefuroxime
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Formulary
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Cefuroxime 250mg injection
Cefuroxime 750mg injection
Cefuroxime 1.5g injection
As per local guideline
Cefuroxime 125mg/5mL oral suspension
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Ertapenem (Invanz®)
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Formulary
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Ertapenem 1g injection
As per local guideline
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Meropenem
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Formulary
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Meropenem 500mg injection
Meropenem 1g injection
As per local guideline
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| 05.01.02.03 |
Other beta-lactums antibiotics |
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Demeclocycline (Ledermycin®)
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Formulary
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Demeclocycline 150 mg capsules ( Used for SIADH)
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Doxycycline
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Formulary
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Doxycycline 50mg capsule
Doxycycline 100mg capsule
Doxycycline 100mg dispersible tablet
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Lymecycline
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Formulary
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Lymecycline 408mg capsule
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Oxytetracycline
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Formulary
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Oxytetracycline 250mg tablet
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Tigecycline (Tygacil®)
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Formulary
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Tigecycline 50mg injection
Restricted antibiotic. As per local guidance
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Amikacin
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Formulary
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Amikacin 100mg/2ml injection
Amikacin 500mg/2ml injection
As per local guideline
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Gentamicin
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Formulary
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Gentamicin 80mg/2ml injection
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Neomycin Sulphate
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Formulary
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Neomycin 500mg tablet
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Tobramycin
(injection)
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Formulary
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Tobramycin 240mg/6ml injection
- restricted to cystic fibrosis patients only
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Azithromycin
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Formulary
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Azithromycin 250mg capsule
Azithromycin 200mg/5ml suspension
As per local guideline
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Clarithromycin
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Formulary
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Clarithromycin 250mg tablet
Clarithromycin 500mg tablet
Clarithromycin 125mg/5ml suspension
Clarithromycin 250mg/5ml suspension
Clarithromycin 500mg injection
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Erythromycin
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Formulary
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Erythromycin 250mg EC tablet
Erythromycin 125mg/5ml SF suspension
Erythromycin 250mg/5ml SF suspension
Erythromycin 500mg/5ml SF suspension
Erythromycin 1g injection
As per local guideline
|
 UKMI Q&A: Erythromycin and Statin Interaction
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| 05.01.06 |
Clindamycin |
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Clindamycin
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Formulary
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Clindamycin 150mg capsule
Clindamycin 300mg/2ml injection
Clindamycin 600mg/4ml injection
As per local guideline
Clindamycin 75 mg/5mL Suspension (Unlicensed medicine)
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| 05.01.07 |
Some other antibacterials |
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Dalbavancin (Xydalba®)
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Formulary
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Dalbavancin (Xydalba®) 500mg
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Fosfomycin
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Formulary
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Fosfomycin 3g sachets
Fosfomycin 40mg/mL injection (Fomicyt®)
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Chloramphenicol
(Systemic)
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Formulary
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Chloramphenicol 1g injection
As per local guideline
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Sodium fusidate
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Formulary
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Fusidate sodium 250mg FC tablet
Fusidic acid 250mg/5ml suspension
Fusidate sodium 500mg injection
As per local guideline
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| 05.01.07 |
Vancomycin and teicoplanin |
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Teicoplanin (Targocid®)
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Formulary
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Teicoplanin 200mg injection
Teicoplanin 400mg injection
As per local guideline
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Vancomycin
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Formulary
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Vancomycin 125mg capsule
Vancomycin 250mg capsule
Vancomycin 500mg injection
Vancomycin 750mg injection
Vancomycin 1g injection
As per local guideline
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| 05.01.07 |
Daptomycin |
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Daptomycin (Cubicin®)
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Formulary
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Daptomycin 350mg injection
Daptomycin 500mg injection
Micro only/Restricted use
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Linezolid
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Formulary
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Linezolid 600mg tablet
Linezolid 100mg/5ml suspension
Linezolid 2mg/ml infusion
Micro only/Restricted use
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| 05.01.07 |
Quinupristin and dalfopristin |
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Colistimethate
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Formulary
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Colistimethate 500, 000unit injection
Colistimethate 1 million unit injection
Micro only/Restricted use
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Rifaximin
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Formulary
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Rifaximin 550mg tablet
As per local guideline
For use in line with NICE guidance TA337 (Rifaximin for preventing episodes of overt hepatic encephalopathy)
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NICE TA337: Rifaximin for preventing episodes of overt hepatic encephalopathy
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| 05.01.07 |
Fidaxomicin |
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| 05.01.08 |
Sulphonamides and trimethoprim |
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Co-trimoxazole
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Formulary
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Co-trimoxazole 480mg tablet
Co-trimoxazole 960mg tablet
Co-trimoxazole 240mg/5ml suspension
Co-trimoxazole 480mg/5ml suspension
Co-trimoxazole 480mg/5ml injection
Co-trimoxazole 960mg/10ml injection
As per local guideline
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UKMI Q&A: How to prepare and administer intravenous co-trimoxazole in fluid restricted patients?
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Trimethoprim
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Formulary
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Trimethoprim 100mg tablet
Trimethoprim 200mg tablet
Trimethoprim 50mg/5ml suspension
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| 05.01.09 |
Antituberculosis drugs |
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Ethambutol
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Formulary
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Ethambutol 100mg tablet
Ethambutol 400mg tablet
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Isoniazid
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Formulary
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Isoniazid 50mg tablet
Isoniazid 100mg tablet
Isoniazid 50mg/2ml injection
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Pyrazinamide
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Formulary
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Pyrazinamide 500mg tablets
Pyrazinamide 500mg/5ml liquid
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Rifabutin (Mycobutin®)
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Formulary
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Rifabutin 150mg capsule
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Rifampicin
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Formulary
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Rifampicin 150mg capsule
Rifampicin 300mg capsule
Rifampicin 100mg/5ml oral syrup
Rifampicin 600mg injection
As per local guideline
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Rifampicin and Isoniazid (Rifinah® 300)
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Formulary
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Rifinah 300 tablet (rifampicin 300mg/isoniazid 150mg)
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Rifampicin and Isoniazid (Rifinah® 150)
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Formulary
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Rifinah 150 tablet (rifampicin 150mg/isoniazid 100mg)
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Rifampicin and Isoniazid and Pyrazinamide (Rifater®)
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Formulary
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Rifater tablet (isoniazid 50mg/pyrazinamide 300mg/rifampicin 120mg)
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Rifampicin, isoniazid, pyrazinamide and ethambutol (Voractiv®)
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Formulary
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Voractiv tablet (ethambutol 275mg/isoniazid 75mg/pyrazinamide 400mg/rifampicin 150mg)
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Streptomycin
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Formulary
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Streptomycin 1g injection
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| 05.01.10 |
Antileprotic drugs |
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Dapsone
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Formulary
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Dapsone 50mg tablet
Dapsone 100mg tablet
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| 05.01.11 |
Metronidazole and tinidazole |
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Metronidazole
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Formulary
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Metronidazole 200mg tablet
Metronidazole 400mg tablet
Metronidazole 200mg/5ml suspension
Metronidazole 500mg suppository
Metronidazole 1g suppository
Metronidazole 500mg/100ml infusion
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Tinidazole (Fasigyn®)
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Formulary
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Tinidazole 500mg tablet
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| 05.01.12 |
Quinolones |
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Ciprofloxacin
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Formulary
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Ciprofloxacin 250mg tablet
Ciprofloxacin 500mg tablet
Ciprofloxacin 250mg/5ml suspension
Ciprofloxacin 100mg/50ml infusion
Ciprofloxacin 200mg/100 infusion
Ciprofloxacin 400mg/200ml infusion
As per local guideline
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Levofloxacin
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Formulary
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Levofloxacin 250mg tablet
Levofloxacin 500mg tablet
Levofloxacin 5mg/ml injection
As per local guideline
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Moxifloxacin
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Formulary
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Moxifloxacin 400mg tablet
AS per local guideline
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Ofloxacin
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Formulary
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Ofloxacin 400mg tablet
As per local guideline
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| 05.01.13 |
Urinary-tract infections |
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Dequalinium Chloride 10mg Vaginal Tablets (Fluomizin®)
(BACTERIAL VAGINOSIS)
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Formulary
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For Bacterial Vagninosis
(Non antibiotic preparation)
Dequalinium Chloride 10mg Vaginal Tablets
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Methenamine Hippurate (Hiprex®)
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Formulary
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Methenamine Hippurate (Hiprex®) 1g tablets
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Nitrofurantoin
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Formulary
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Nitrofurantoin 50mg tablet
Nitrofurantoin 25mg/5ml suspension
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Amphotericin (AmBisome®)
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Formulary
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Amphotericin B Liposomal (Ambisome)50mg Injection
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Fluconazole
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Formulary
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Fluconazole 50mg capsule
Fluconazole 150mg capsule
Fluconazole 200mg capsule
Fluconazole 50mg/5ml suspension
Fluconazole 200mg/5ml suspension
Fluconazole 2mg/ml injection
|
UKMI Q&A: Can oral fluconazole be used with breastfeeding?
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Flucytosine (Ancotil®)
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Formulary
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Flucytosine 2.5g/250ml infusion
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Griseofulvin
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Formulary
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Griseofulvin 125mg tablet
Griseofulvin 125mg/5ml oral suspension
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Itraconazole
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Formulary
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Itraconazole 100mg capsule
Itraconazole 10mg/ml oral solution
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Ketoconazole
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Formulary
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Ketoconazole 200mg tablet
Ketoconazole 100mg/5ml oral liquid
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Posaconazole (oral) (Noxafil®)
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Formulary
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Posaconazole 100mg capsule
Posaconazole 40mg/ml suspension
Posaconazole 300mg concentrate for solution for infusion
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Terbinafine
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Formulary
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Terbinafine 250mg tablet
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Voriconazole (Vfend®)
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Formulary
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Voriconazole 200mg tablet
Voriconazole 200mg/5ml oral suspension
Voriconazole 200mg injection
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| 05.02 |
Drugs used in fungal infections |
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Nystatin (Nystan®)
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Formulary
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Nystatin 500,000 units tablet
Nystatin 100,000 units/ml suspension
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| 05.02.01 |
Triazole antifungals |
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Isavuconazole (Cresemba®)
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Formulary
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Isavuconazole 100mg capsules (Cresemba®)
Isavuconazole 200mg injection (Cresemba®)
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| 05.02.02 |
Imidazole antifungals |
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| 05.02.03 |
Polyene antifungals |
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| 05.02.04 |
Echinocandin antifungals |
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Anidulafungin
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First Choice
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Caspofungin (Cancidas®)
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Formulary
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Caspofungin 50mg injection
Caspofungin 70mg injection
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Micafungin (Mycamine®)
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Formulary
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Micafungin 50mg powder for infusion (Mycamine®)
Micro only/Restricted use
Micafungin 100 mg powder for infusion (Mycamine) micro only/Restricted use
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Albendazole
|
 Unlicensed
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Albendazole tablet
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| 05.02.05 |
Other antifungals |
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| 05.03.01 |
HIV infection |
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| 05.03.01 |
Nucleoside reverse transcriptase inhibitors |
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Abacavir (Ziagen®)
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Formulary
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Abacavir 300mg tablet (Ziagen®)
Abacavir 20mg/ml oral solution (Ziagen®)
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Abacavir 300mg, Lamivudine 150mg and Zidovudine 300mg tablet (Trizivir®)
(tablet)
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Formulary
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Trizivir tablet
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Abacavir, Lamivudine and Dolutegravir (Triumeq®)
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Formulary
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Abacavir 600 mg, Dolutegravir 50 mg, Lamivudine 300 mg tablet (Triumeq®)
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Darunavir/Cobicistat/Emtricitabine/Tenofovir (Symtuza®)
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Formulary
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Symtuza® (Darunavir 800mg/Cobicistat 150mg/Emtricitabine 200mg/Tenofovir 10mg)
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Didanosine (Videx®)
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Formulary
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Didanosine 125mg EC capsule (Videx®)
Didanosine 200mg EC capsule (Videx®)
Didanosine 250mg EC capsule (Videx®)
Didanosine 400mg EC capsule (Videx®)
Didanosine 200mg tablet (Videx®)
Didanosine suspension (Videx®)
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Efavirenz 600mg, Emtricitabine 200mg and Tenofovir 245mg tablet (Atripla®)
(tablet)
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Formulary
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Atripla 600mg/200mg/245mg tablet
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Emtricitabine 200mg (Emtriva®)
(capsule)
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Formulary
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Emtricitabine 200mg capsule
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Emtricitabine 200mg, Rilpivirine 25mg and Tenofovir 245mg tablet (Eviplera®)
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Formulary
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Eviplera tablet
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Lamivudine
(tablet/ oral solution)
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Formulary
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Lamivudine 100mg tablet
Lamivudine 150mg tablet
Lamivudine 300mg tablet
Lamivudine 10mg/ml oral solution (Epivir®)
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Lamivudine 150mg / Zidovudine 300mg tablet
(tablet)
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Formulary
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Lamivudine 150mg / Zidovudine 300mg tablet
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Stavudine (Zerit®)
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Formulary
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Stavudine 20mg capsule (Zerit®)
Stavudine 30mg capsule (Zerit®)
Stavudine 40mg capsule (Zerit®)
Stavudine 1mg/ml oral solution (Zerit®)
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Tenofovir 245mg and Emtricitabine 200mg tablet (Truvada®)
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Formulary
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Truvada 200/245mg tablet
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Tenofovir 245mg, cobicistat 150mg, elvitegravir 150mg and emtricitabine 200mg tablet (Stribild®)
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Formulary
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Stribild) tenofovir, cobicistat, elvitegravir and emtricitabine) tablet
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Tenofovir Disproxil (Viread®)
(tablet)
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Formulary
|
Tenofovir disoproxil 245mg tablet
For use in line with NICE TA173: Tenofovir disoproxil for the treatment of chronic hepatitis
|
NICE CG165: Hepatitis B (chronic) - incorporates TA173
NICE TA173: Hepatitis B (chronic) - tenofovir disoproxil
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Zidovudine
(capsule/oral solution/injection)
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Formulary
|
Zidovudine 100mg capsule
Zidovudine 250mg capsule
Zidovudine 10mg/ml oral solution(Retrovir®)
Zidovudine 200mg/20ml injection(Retrovir®)
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Didanosine 10mg/ml oral liquid
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Unlicensed
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Didanosine 10mg/ml oral liquid
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| 05.03.01 |
Protease inhibitors |
|
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Amprenavir (Agenerase®)
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Formulary
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Amprenavir capsule
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Atazanavir (Reyataz®)
|
Formulary
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Atazanavir 150mg capsule(Reyataz®)
Atazanavir 200mg capsule(Reyataz®)
Atazanavir 300mg capsule(Reyataz®)
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Atazanavir & Cobicistat (Evotaz®)
|
Formulary
|
Evotaz® (Atazanavir 300mg / Cobicistat 150mg) film coated tablet
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Darunavir (Prezista®)
|
Formulary
|
Darunavir 300mg tablet(Prezista®)
Darunavir 400mg tablet(Prezista®)
Darunavir 600mg tablet(Prezista®)
Darunavir 800mg tablet(Prezista®)
Daunavir 500 mg/ 5mL Liquid
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Darunavir & Cobicistat (Rezolsta®)
|
Formulary
|
Rezolsta® (Darunavir 800mg/Cobicistat 150mg) film coated tablet
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Fosamprenavir (Telzir®)
|
Formulary
|
Fosamprenavir 700mg tablet
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Indinavir (Crixivan®)
(capsule)
|
Formulary
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Indinavir 200mg capsule(Crixivan®)
Indinavir 400mg capsule(Crixivan®)
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Lopinavir and Ritonavir (Kaletra®)
(tablet/oral liquid)
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Formulary
|
Lopinavir and Ritonavir 100mg/25mg (Kaletra®) tablet
Lopinavir and Ritonavir 200mg/50mg (Kaletra®) tablet
Lopinavir and Ritonavir 400mg+100mg/5ml (Kaletra®) oral liquid
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Nelfinavir (Viracept®)
|
Formulary
|
Nelfinavir 250mg tablet
|
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Ritonavir (Norvir®)
|
Formulary
|
Ritonavir 100mg tablet (Norvir®)
Ritonavir 400mg/5ml oral liquid (Norvir®)
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Saquinavir (Invirase®)
|
Formulary
|
Saquinavir 500mg tablet (Invirase®)
|
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Tipranavir (Aptivus®)
|
Formulary
|
Tipranavir 250mg capsule (Aptivus ®)
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|
| 05.03.01 |
Non-nucleoside reverse transcriptase inhibitors |
|
|
Efavirenz
(tablet/capsule/oral liquid)
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Formulary
|
Efavirenz 200mg capsule (Sustiva®)
Efavirenz 600mg tablet
Efavirenz 30mg/ml oral liquid
|
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Etravirine (Intelence®)
|
Formulary
|
Etravirine 100mg tablet (Intelence®)
Etravirine 200mg tablet (Intelence®)
|
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Nevirapine
(tablet/oral suspension)
|
Formulary
|
Nevirapine 200mg tablet
Nevirapine 50mg/5ml oral suspension (Viramune®)
Nevirapine 400mg XR tablet (Viramune®)
|
|
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Rilpivirine hydrochloride (Edurant®)
|
Formulary
|
Rilpivirine 25mg tablet (Edurant®)
|
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|
| 05.03.01 |
Other antiretrovirals |
|
|
Dolutegravir (Tivicay®)
|
Formulary
|
Dolutegravir 50mg tablet (Tivicay®)
|
|
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Enfuvirtide (Fuzeon®)
|
Formulary
|
Enfuvirtide 90mg/ml injection
|
|
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Maraviroc (Celsentri®)
|
Formulary
|
Maraviroc 150mg tablet (Celsentri®)
Maraviroc 300mg tablet (Celsentri®)
|
|
|
Raltegravir (Isentress ®)
(tablet)
|
Formulary
|
Raltegravir 400mg tablet (Isentress®)
Raltegravir 600mg tablet (Isentress®)
Raltegravir 100mg granules (Isentress®)
|
|
|
| 05.03.02 |
Herpesvirus infections |
|
|
| 05.03.02.01 |
Herpes simplex and varicella-zoster infection |
|
|
Aciclovir
|
Formulary
|
Aciclovir 200mg tablet
Aciclovir 400mg tablet
Aciclovir 800mg tablet
Aciclovir 200mg/5ml suspension
Aciclovir 400mg/5ml suspension
Aciclovir 500mg injection
|
|
|
Famciclovir
(tablet)
|
Formulary
|
Famciclovir 250mg tablet
|
|
|
Inosine Pranobex (Imunovir®)
|
Formulary
|
Inosine pranobex 500mg tablet (Imunovir®)
|
|
|
Valaciclovir
(tablet)
|
Formulary
|
Valaciclovir 250mg tablet (Valtrex®)
Valaciclovir 500mg tablet
|
|
|
| 05.03.02.02 |
Cytomegalovirus infection |
|
|
Cidofovir infusion (Vistide®)
|
Formulary
|
Cidofovir 375mg/5ml injection
|
|
|
Foscarnet Sodium Infusion (Foscavir®)
|
Formulary
|
Foscarnet sodium 24 mg/ml infusion (Foscavir®)
|
|
|
Ganciclovir (Cymevene®)
(capsule/infusion)
|
Formulary
|
Ganciclovir 250mg capsule (Cymevene®)
Ganciclovir 500mg capsule (Cymevene®)
Ganciclovir 500mg injection (Cymevene®)
|
|
|
Valganciclovir tablet (Valcyte®)
(tablet)
|
Formulary
|
Valganciclovir 450mg tablet (Valcyte®)
|
|
|
Ganciclovir 4.5mg implant
|
Unlicensed
|
Ganciclovir 4.5mg implant
|
|
|
|
|
| 05.03.03.01 |
Chronic hepatitis B |
|
|
Adefovir Dipivoxil (Hepsera®)
(tablet)
|
Formulary
|
Adefovir Dipivoxil 10mg tablet (Hepsera®)
For use in line with NICE TA96: Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B
|
 NICE CG165: Hepatitis B (chronic) - incorporates TA96
NICE TA96: Hepatitis B (chronic) - adefovir dipivoxil and pegylated interferon alpha-2a
|
Entecavir (Baraclude®)
|
Formulary
|
Entecavir 500mcg tablet (Baraclude®)
Entecavir 1mg tablet (Baraclude®)
Entecavir 50mcg/ml oral solution (Baraclude®)
For use in line with NICE TA153: Entecavir for the treatment of chronic hepatitis B
|
NICE CG165: Hepatitis B (incorporates TA153)
NICE TA153: Hepatitis B (chronic) - entecavir
|
| 05.03.03.02 |
Chronic hepatitis C |
|
|
Boceprevir (Victrelis®)
|
Formulary
|
Boceprevir (Victrelis®) 200mg capsule
For use in line with NICE TA253 (Boceprevir for the treatment of genotype 1 chronic hepatitis C)
|
NICE TA253: Boceprevir for the treatment of genotype 1 chronic hepatitis C
|
Daclatasvir (Daklinza®)
|
Formulary
|
Daclatasvir (Daklinza®) 60mg tablet
For use in line with NICE TA364 (Daclatasvir for treating chronic hepatitis C)
|
NICE TA364: Daclatasvir for treating chronic hepatitis C
|
Dasabuvir (Exviera®)
|
Formulary
|
Dasabuvir (Exviera®) 250mg film coated tablet
For use in line with NICE TA365 (Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis C)
|
NICE TA365: Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis C
|
Elbasvir/Grazoprevir (Zepatier®)
|
Formulary
|
Zepatier® (Elbasvir 50mg/Grazoprevir 100mg) film coated tablet
For use in line with NICE TA413 (Elbasvir–grazoprevir for treating chronic hepatitis C)
|
NICE TA413: Elbasvir–grazoprevir for treating chronic hepatitis C
|
Glecaprevir/pibrentasvir (Maviret®)
|
Formulary
|
Glecaprevir 100mg/pibrentasvir 40mg (Maviret®) film-coated tablets
For use in line with NICE TA499 - Glecaprevir–pibrentasvir for treating chronic hepatitis C
|
|
|
Harvoni (Harvoni®)
|
Formulary
|
Harvoni® (ledipasvir 90mg / sofosbuvir 400mg) film coated tablet
For use in line with NICE TA363 (Ledipasvir–sofosbuvir for treating chronic hepatitis C)
|
NICE TA363: Ledipasvir–sofosbuvir for treating chronic hepatitis C
|
Ombitasvir/ paritaprevir/ritonavir (Viekirax®)
|
Formulary
|
Viekirax® (12.5mg ombitasvir/75mg paritaprevir/50mg ritonavir) film coated tablet
For use in line with NICE TA365 (Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis C)
|
NICE TA365: Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis C
|
Sofosbuvir (Sovaldi®)
|
Formulary
|
Sofosbuvir 400mg tablet (Sovaldi®)
For use in line with NICE TA330 (Sofosbuvir for treating chronic hepatitis C)
|
NICE TA330: Sofosbuvir for treating chronic hepatitis C
|
Sofosbuvir /Velpatasvir (Epclusa®)
|
Formulary
|
Sofosbuvir 400mg/Velpatasvir (Epclusa®) 100mg tablets
For use in line with NICE TA430 (Sofosbuvir-Velpatasvir for treating chronic hepatitis C)
|
NICE TA430: Sofosbuvir–velpatasvir for treating chronic hepatitis C
|
sofosbuvir/velpatasvir/voxilaprevir (Vosevi®)
|
Formulary
|
Sofosbuvir 400mg/velpatasvir 100mg/ voxilaprevir (Vosevi®) 100mg film coated tablets
For use in line with NICE TA507 - Sofosbuvir–velpatasvir–voxilaprevir for treating chronic hepatitis C
|
|
|
Telaprevir (Incivo®)
|
Formulary
|
Telaprevir 375mg tablet (Incivo®)
Use in line with NICE TA252 (Telaprevir for the treatment of genotype 1 chronic hepatitis C)
|
NICE TA252: Telaprevir for the treatment of genotype 1 chronic hepatitis C
|
|
|
Amantadine
(Influenza)
|
Formulary
|
Amantadine 100mg capsule
For use in line with NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
|
NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
|
Oseltamivir
|
Formulary
|
Oseltamivir 30mg capsules(Tamiflu®)
Oseltamivir 45mg capsules(Tamiflu®)
Oseltamivir 75mg capsules(Tamiflu®)
Oseltamivir 6mg/ml oral solution(Tamiflu®)
Oseltamivir 15mg/ml oral solution - under 1yr old
For use in line with NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
|
NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
UKMI Q&A: Can mothers breastfeed after taking oseltamivir and zanamivir
UKMI Q&A: Can oseltamivir be taken by patients taking methotrexate?
|
Zanamivir inhalation (Relenza®)
|
Formulary
|
Zanamivir 5mg diskhaler (Relenza®)
For use in line with NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
|
NICE TA158: Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza
|
|
|
|
|
|
|
|
|
| 05.03.05 |
Respiratory syncytial virus |
|
|
Palivizumab (Synagis®)
(Injection)
|
Formulary
|
Palivizumab 50mg injection(Synagis®)
Palivizumab 100mg injection(Synagis®)
|
|
|
Ribavirin (Copegus®)
|
Formulary
|
Ribavirin 200mg tablet (Copegus®)
Ribavirin 400mg tablet (Copegus®)
|
|
|
Ribavirin (Rebetol®)
|
Formulary
|
Ribavirin 200mg capsule (Rebetol®)
|
|
|
| 05.04 |
Antiprotozoal drugs |
|
|
Paromomycin
|
Unlicensed
|
Paromomycin 250mg tablet
|
|
|
|
|
|
|
|
|
| 05.04.01 |
Treatment of malaria |
|
|
Artesunate
|
Unlicensed
|
Artesunate 60mg injection
|
|
|
| 05.04.01 |
Falciparum malaria (treatment) |
|
|
| 05.04.01 |
Benign malarias (treatment) |
|
|
| 05.04.01 |
Prophylaxis against malaria |
|
|
| 05.04.01 |
Specific recommendations |
|
|
| 05.04.01 |
Artemether with lumefabtrine |
|
|
Artemether with lumefantrine (Riamet®)
|
Formulary
|
Artemether with lumefantrine 20mg/120mg tablets
|
|
|
|
|
Chloroquine
|
Formulary
|
Chloroquine 250mg tablet
|
|
|
|
|
Mefloquine (Lariam®)
|
Formulary
|
Mefloquine 250mg tablet
|
|
|
|
|
Primaquine
|
Formulary
|
Primaquine 7.5mg tablet
Reserved: for specialist use only or following medical microbiology advice
|
|
|
|
|
Proguanil Hydrochloride (Paludrine®)
|
Formulary
|
Proguanil 100mg tablet
|
|
|
Proguanil Hydrochloride with Atovaquone (Malarone®)
|
Formulary
|
Proguanil hydrochloride with atovaquone (Malarone®) tablet
|
|
|
| 05.04.01 |
Pyrimethamine |
|
|
Pyrimethamine (Darprim®)
|
Formulary
|
Pyrimethamine 25mg tablet
|
|
|
Pyrimethamine with Sulfadoxine (Fansidar®)
|
Formulary
|
Pyrimethamine with sulfadoxine (Fansidar) tablet
|
|
|
|
|
Quinine
(malaria)
|
Formulary
|
Quinine dihydrochloride 300mg/ml injection
Quinine sulphate 200mg tablet
Quinine sulphate 300mg tablet
|
|
|
|
|
Doxycycline
|
Formulary
|
Doxycycline 50mg capsule
Doxycycline 100mg capsule
Doxycycline 100mg dispersible tablet
|
|
|
|
|
Diloxanide
|
Formulary
|
Dilanoxide 500mg tablet
|
|
|
Metronidazole
(amoebic dysentry)
|
Formulary
|
Metronidazole 400mg tablet
|
|
|
Tinidazole
|
Formulary
|
Tinidazole 500mg tablet
|
|
|
|
|
Metronidazole
(Trichomonacides)
|
Formulary
|
Metronidazole 400mg tablet
|
|
|
| 05.04.04 |
Antigiardial drugs |
|
|
Mepacrine Hydrochloride
|
Formulary
|
Mepacrine 100mg tablet
|
|
|
|
|
|
|
| 05.04.07 |
Drugs for toxoplasmosis |
|
|
| 05.04.08 |
Drugs for pneumocystis pneumonia |
|
|
Atovaquone (Wellvone®)
|
Formulary
|
Atovaquone 750mg/5ml suspension
Reserved: for specialist use only or following medical microbiology advice
|
|
|
Pentamidine Isetionate (Pantacarinat®)
|
Formulary
|
Pentamidine 300mg injection
Pentamidine 300mg/5ml nebule
Reserved: for specialist use only or following medical microbiology advice
|
|
|
| 05.04.08 |
Treatment |
|
|
|
|
|
|
Levamisole
|
Unlicensed
|
Levamisole tablet
|
|
|
| 05.05.01 |
Drugs for threadworms |
|
|
Mebendazole
|
Formulary
|
Mebendazole 100mg tablet
Mebendazole 100mg/5ml suspension
|
|
|
|
|
|
|
| 05.05.03 |
Drugs for tapeworm infections |
|
|
|
|
|
|
| 05.05.04 |
Drugs for hookworms |
|
|
| 05.05.05 |
Schistosomicides |
|
|
Pranziquantel
|
Unlicensed
|
Praziquantel 500mg tablet
Praziquantel 600mg tablet
|
|
|
| 05.05.06 |
Filaricides |
|
|
| 05.05.07 |
Drugs for cutaneous larva migrans |
|
|
| 05.05.08 |
Drugs for strongyloidiasis |
|
|
| .... |
| Non Formulary Items |
Minocycline
|
Non Formulary
|
Minocycline 100mg SR capsule
Non-formulary |
|
|
Quinupristin and dalfopristin (Synercid®)
|
Non Formulary
|
|
|
|
| |
Key |
|
|
|
|
Cytotoxic Drug
|
|
|
Controlled Drug
|
|
High Cost Medicine
|
|
Cancer Drugs Fund
|
|
NHS England |
|
Homecare |
|
CCG |
|
Traffic Light Status Information
| Status |
Description |
|
Formulary |
|
Nice Approved / Formulary |
|
NICE approved |
|
Amber Restricted Use |
|
Non Formulary |
|
|
|
