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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
08.02.04  Expand sub section  Other immunomodulating drugs
Avelumab (Bravencio®)
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Formulary
NICE Formulary
High Cost Medicine

Avelumab 200mg/10ml concentrate for solution for infusion vials

For use in line with NICE TA517 - Avelumab for treating metastatic Merkel Cell Carcinoma

 

 
   
Dimethyl fumarate (Tecfidera®)
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Formulary
NICE Formulary
High Cost Medicine
Dimethyl Fumarate (Tecfidera) 120mg capsule
Dimethyl Fumarate (Tecfidera) 240mg capsule
For use in line with NICE TA320 (Dimethyl fumarate for treating relapsing‑remitting multiple sclerosis)

 
Link  NICE TA320: Dimethyl fumarate for treating relapsing‑remitting multiple sclerosis
   
Fingolimod (Gilenya®)
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Formulary
NICE Formulary
High Cost Medicine
Fingolimod 500mcg capsule
For use in line with NICE TA254 (Fingolimod for the treatment of highly active relapsing–remitting multiple sclerosis)
 
Link  NICE TA254: Fingolimod for highly active relapsing remitting multiple sclerosis
   
Interferon Gamma (Immukin )
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Formulary
On Formulary
Immukin 100micrograms/0.5ml solution for injection vials  
   
Lenalidomide ( Revlimid®)
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Formulary
NICE Formulary
High Cost Medicine
Cancer Drugs Fund

Lenalidomide 5mg capsule
Lenalidomide 10mg capsule
Lenalidomide 15mg capsule
Lenalidomide 25mg capsule
For use in line with NICE TA171 (Lenalidomide for the treatment of multiple myeloma in people who have received at least one prior therapy)
For use in line with NICE TA322 (Lenalidomide for treating myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality)

For use in line with NICE TA586 (Lenalidomide plus dexamethasone for multiple myeloma after 1 treatment with bortezomib)

For use in line with NICE TA587 (Lenalidomide plus dexamethasone for previously untreated multiple myeloma)

 
Link  NICE TA171: Multiple myeloma - lenalidomide
Link  NICE TA322: Lenalidomide for treating myelodysplastic syndromes associated with an isolated deletion 5q cytogenetic abnormality
   
Nivolumab (Opdivo®)
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Formulary
NICE Formulary
High Cost Medicine

Nivolumab (Opdivo®) 10 mg/mL concentrate for solution for infusion.

For use in line with NICE TA384 (Nivolumab for treating advanced (unresectable or metastatic) melanoma)
For use in line with NICE TA400 (Nivolumab in combination with ipilimumab for treating advanced melanoma)
For use in line with NICE TA417 (Nivolumab for previously treated advanced renal cell carcinoma)
For use in line with NICE TA462 (Nivolumab for treating relapsed or refractory classical Hodgkin lymphoma)
For use in line with NICE TA483 (Nivolumab for previously treated squamous non-small-cell lung cancer)
For use in line with NICE TA484 (Nivolumab for previously treated non-squamous non-small-cell lung cancer)

For use in line with NICE TA581 (Nivolumab with ipilimumab for untreated advanced renal cell carcinoma)

 
Link  NICE TA384: Nivolumab for treating advanced (unresectable or metastatic) melanoma
Link  NICE TA400: Nivolumab in combination with ipilimumab for treating advanced melanoma
Link  NICE TA417: Nivolumab for previously treated advanced renal cell carcinoma
   
Pomalidomide (Imnovid®)
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Formulary
NICE Formulary
High Cost Medicine
Cancer Drugs Fund
Pomalidomide 1mg capsule
Pomalidomide 2mg capsule
Pomalidomide 3mg capsule
Pomalidomide 4mg capsule
For use in line with NICE TA338 (Pomalidomide for relapsed and refractory multiple myeloma previously treated with lenalidomide and bortezomib)
For use in line with NICE TA427 (Pomalidomide for multiple myeloma previously treated with lenalidomide and bortezomib)
 
Link  NICE TA338: Pomalidomide for relapsed and refractory multiple myeloma previously treated with lenalidomide and bortezomib
Link  NICE TA427: Pomalidomide for multiple myeloma previously treated with lenalidomide and bortezomib
   
Teriflunomide (Aubagio®)
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Formulary
NICE Formulary
High Cost Medicine
Teriflunomide 14mg tablets
For use in line with NICE TA303 (Teriflunomide for treating relapsing–remitting multiple sclerosis)
 
Link  NICE TA303: Teriflunomide for relapsing remitting MS
   
Thalidomide (Celgene®)
(haematology)
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Formulary
NICE Formulary
High Cost Medicine
Thalidomide 50mg capsule
For use in line with NICE TA228 (Bortezomib and thalidomide for the first‑line treatment of multiple myeloma)
 
Link  NICE TA228: Bortezomib and thalidomide for the first‑line treatment of multiple myeloma
   
08.02.04  Expand sub section  Interferon Alfa
Interferon Alfa (IntronA)
(injection/pen)
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Formulary
On Formulary
High Cost Medicine
Interferon (Intron A) 10MU injection
Interferon (Intron A) 18MU/1.2ml pen
Interferon (Intron A) 30MU/1.2ml pen
 
   
Interferon Alfa (Roferon-A®)
(syringe/cartridge)
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Formulary
On Formulary
High Cost Medicine
Interferon (Roferon A) 3MU/0.5ml syringe
Interferon (Roferon A) 4.5MU/0.5ml syringe
Interferon (Roferon A) 6MU/0.5ml syringe
Interferon (Roferon A) 18MU/0.6ml cartridge
 
   
Peginterferon Alfa
(pen/injection)
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Formulary
NICE Formulary
High Cost Medicine
Interferon (Viraferon PEG) 80mcg pen
Interferon (Viraferon PEG) 100mcg pen
Interferon (Viraferon PEG) 120mcg pen
Interferon (Viraferon PEG) 150mcg pen
Interferon Pegylated 80mcg injection
For use in line with NICE TA106: Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis
 
Link  NICE TA106: Hepatitis C - peginterferon alfa and ribavirin
Link  NICE TA200: Hepatitis C - peginterferon alfa and ribavirin
Link  NICE TA300: Hepatitis C (children and young people) - peginterferon alfa and ribavirin
Link  NICE TA75: Hepatitis C - pegylated interferons, ribavirin and alfa interferon
   
Peginterferon beta-1a (Plegridy®)
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Formulary
Red Hospital
High Cost Medicine
Peginterferon beta-1a (Plegridy®) Initiation pack
[Plegridy 63 micrograms solution for injection in pre-filled pen
Plegridy 94 micrograms solution for injection in pre-filled pen]
Peginterferon beta-1a (Plegridy®) 125 micrograms solution for injection in pre-filled pen 
   
08.02.04  Expand sub section  Interferon beta
Interferon beta (Extavia®)
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Formulary
NICE Formulary
High Cost Medicine
NHS England

Interferon Beta (Extavia®) solution for injection

For use in line with NICE TA527 (Beta interferon (Extavia) for treating multiple sclerosis)

 
   
08.02.04  Expand sub section  Aldesleukin
Aldesleukin (Proleukin®)
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Formulary
On Formulary
High Cost Medicine
Aldesleukin 18MU injection
 
   
08.02.04  Expand sub section  Glatiramer acetate to top
Glatiramer Acetate (Copaxone®)
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Formulary
NICE Formulary
High Cost Medicine
Glatiramer Acetate (Copaxone®) 40mg/ml prefilled syringe
For use in line with NICE TA32: Beta interferon and glatiramer acetate for the treatment of multiple sclerosis 
Link  NICE TA32: Beta interferon and glatiramer acetate for the treatment of multiple sclerosis
   
08.02.04  Expand sub section  Natalizumab
Natalizumab (Tysabri®)
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Restricted Drug Restricted
NICE Formulary
High Cost Medicine
Natalizumab 300mg/15ml injection
For use in line with NICE TA127: Natalizumab for the treatment of adults with highly active relapsing–remitting multiple sclerosis  
Link  NICE TA127: Multiple sclerosis - natalizumab
   
 ....
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note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

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On Formulary

Formulary  

NICE Formulary

Nice Approved / Formulary  

NICE Approved

NICE approved  

Amber Restricted

Amber Restricted Use  

Non Formulary

Non Formulary  

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